盧華定,男,主任醫師,副教授,博士研究生,博士研究生導師,廣東省人體生物組織工程學會常務理事兼副秘書長,廣東省醫學會關節外科青年委員、廣東省醫學會骨質疏松分會基礎學組委員、廣東省健康管理協會委員。從事骨科臨床工作和研究20多年,獲醫學博士學位,曾去德國Ludiwigshafen 骨科創傷中心進修,獲 AO Fellowship 證書。對各種骨關節創傷、關節退行性病變、股骨頭壞死,骨腫瘤、慢性骨髓炎、肢體畸形矯形及老年性骨質疏松癥等積累了豐富的臨床經驗。擅長髖、膝、肩關節置換手術;股骨頭壞死的診治;四肢及骨盆的嚴重骨與關節損傷、髖、膝、踝關節周圍骨折的手術治療;應用關節鏡治療各種關節疾患及關節運動創傷,對肢體畸形;慢性骨髓炎;良、惡性腫瘤等的診治也有豐富的經驗,對老年骨質疏松癥的診治亦有深入的研究。發表SCI收錄論著10余篇,在國家核心期刊發表論文50余篇,主持3項國家自然科學基金、5項廣東省級基金等課題的研究,并參加國家 863計劃、廣東省科技廳重點攻關課題研究。
論著:(*為通訊作者)
1)Lu H*, Zhu L, Lian L, Chen M, Shi D, Wang K. PGC-1α regulates the expression and activity of IRF-1. IUBMB Life. 2015 Apr 15. doi: 10.1002/iub.1369. [Epub ahead of print] SCI收錄 IF: 2.755
2)Lu H*, Zhu L, Lian L, Chen M, Shi D, Wang K. Genetic variations in the PRKCG gene and osteosarcoma risk in a Chinese population: a case-control study. Tumour Biol. 2015 Feb 9. [Epub ahead of print] SCI收錄 IF: 2.84
3)Lu H*, Zeng C, Zhao H, Lian L, Dai Y. Glatiramer acetate inhibits degradation of collagen II by suppressing the activity of interferon regulatory factor-1. Biochem Biophys Res Commun. 2014; 448(3): 323-328. SCI收錄 IF: 2.281
4)Lu H*, Dai Y, Lv L, Zhao H. Chitosan-graft-polyethylenimine/DNA nanoparticles as novel non-viral gene delivery vectors targeting osteoarthritis. PLoS One. 2014; 9(1): e84703. SCI收錄 IF: 3.534
5)Lu H*, Hou G, Zhang Y, Dai Y, Zhao H. c-Jun transactivates Puma gene expression to promote osteoarthritis. Mol Med Rep. 2014; 9(5):1606-1612. SCI收錄 IF: 1.484
6)Hou G, Lu HD*, Chen MJ, Yao H, Zhao HQ. Oxidative Stress Participates in Age-related changes in Rat Lumbar Intervertebral Discs. Arch Gerontol Geriatr. 2014; 59: 665-669. SCI收錄 IF: 1.525
7)Lu HD*, Lian LY, Shi DH, Zhao HQ, Dai YH. Hepcidin Promotes Osteogenic Differentiation through BMP2/SMAD and MAPK/P38 Signaling pathways in Mesenchymal stem cells. Mol Med Rep. 2015; 11: 143-150. SCI收錄 IF: 1.484
8)Lu HD*, Zhao HQ, Wang K, Lv LL. Novel hyaluronic acid-chitosan nanoparticles as non-viral gene delivery vectors targeting osteoarthritis. Int ...
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