盧華定主任醫(yī)師

盧華定，男，主任醫(yī)師，副教授，博士研究生，博士研究生導(dǎo)師，廣東省人體生物組織工程學(xué)會常務(wù)理事兼副秘書長，廣東省醫(yī)學(xué)會關(guān)節(jié)外科青年委員、廣東省醫(yī)學(xué)會骨質(zhì)疏松分會基礎(chǔ)學(xué)組委員、廣東省健康管理協(xié)會委員。從事骨科臨床工作和研究20多年，獲醫(yī)學(xué)博士學(xué)位，曾去德國Ludiwigshafen 骨科創(chuàng)傷中心進(jìn)修，獲 AO Fellowship 證書。對各種骨關(guān)節(jié)創(chuàng)傷、關(guān)節(jié)退行性病變、股骨頭壞死，骨腫瘤、慢性骨髓炎、肢體畸形矯形及老年性骨質(zhì)疏松癥等積累了豐富的臨床經(jīng)驗(yàn)。擅長髖、膝、肩關(guān)節(jié)置換手術(shù)；股骨頭壞死的診治；四肢及骨盆的嚴(yán)重骨與關(guān)節(jié)損傷、髖、膝、踝關(guān)節(jié)周圍骨折的手術(shù)治療；應(yīng)用關(guān)節(jié)鏡治療各種關(guān)節(jié)疾患及關(guān)節(jié)運(yùn)動創(chuàng)傷，對肢體畸形；慢性骨髓炎；良、惡性腫瘤等的診治也有豐富的經(jīng)驗(yàn)，對老年骨質(zhì)疏松癥的診治亦有深入的研究。發(fā)表SCI收錄論著10余篇，在國家核心期刊發(fā)表論文50余篇，主持3項(xiàng)國家自然科學(xué)基金、5項(xiàng)廣東省級基金等課題的研究，并參加國家 863計(jì)劃、廣東省科技廳重點(diǎn)攻關(guān)課題研究。 論著:（*為通訊作者） 1)Lu H*, Zhu L, Lian L, Chen M, Shi D, Wang K. PGC-1α regulates the expression and activity of IRF-1. IUBMB Life. 2015 Apr 15. doi: 10.1002/iub.1369. [Epub ahead of print] SCI收錄 IF: 2.755 2)Lu H*, Zhu L, Lian L, Chen M, Shi D, Wang K. Genetic variations in the PRKCG gene and osteosarcoma risk in a Chinese population: a case-control study. Tumour Biol. 2015 Feb 9. [Epub ahead of print] SCI收錄 IF: 2.84 3)Lu H*, Zeng C, Zhao H, Lian L, Dai Y. Glatiramer acetate inhibits degradation of collagen II by suppressing the activity of interferon regulatory factor-1. Biochem Biophys Res Commun. 2014; 448(3): 323-328. SCI收錄 IF: 2.281 4)Lu H*, Dai Y, Lv L, Zhao H. Chitosan-graft-polyethylenimine/DNA nanoparticles as novel non-viral gene delivery vectors targeting osteoarthritis. PLoS One. 2014; 9(1): e84703. SCI收錄 IF: 3.534 5)Lu H*, Hou G, Zhang Y, Dai Y, Zhao H. c-Jun transactivates Puma gene expression to promote osteoarthritis. Mol Med Rep. 2014; 9(5):1606-1612. SCI收錄 IF: 1.484 6)Hou G, Lu HD*, Chen MJ, Yao H, Zhao HQ. Oxidative Stress Participates in Age-related changes in Rat Lumbar Intervertebral Discs. Arch Gerontol Geriatr. 2014; 59: 665-669. SCI收錄 IF: 1.525 7)Lu HD*, Lian LY, Shi DH, Zhao HQ, Dai YH. Hepcidin Promotes Osteogenic Differentiation through BMP2/SMAD and MAPK/P38 Signaling pathways in Mesenchymal stem cells. Mol Med Rep. 2015; 11: 143-150. SCI收錄 IF: 1.484 8)Lu HD*, Zhao HQ, Wang K, Lv LL. Novel hyaluronic acid-chitosan nanoparticles as non-viral gene delivery vectors targeting osteoarthritis. Int

1. 擅長髖、膝、肩關(guān)節(jié)置換手術(shù)； 2. 肩、膝關(guān)節(jié)鏡手術(shù) 3. 骨關(guān)節(jié)炎、股骨頭壞死 其它治療包括：四肢及骨盆的骨與關(guān)節(jié)損傷、髖、膝、踝關(guān)節(jié)周圍骨折的手術(shù)治療；擅長肩、膝、踝關(guān)節(jié)的急慢性運(yùn)動損傷和炎癥的關(guān)節(jié)鏡下修復(fù)重建；對老年骨質(zhì)疏松性骨折等積累了豐富的臨床經(jīng)驗(yàn)